It sounds like you’ve been through a lot since your diagnosis, especially with the initial misdiagnosis and the impact on your kidneys. Rib pain is a common symptom in paraproteinaemia and related conditions, and it’s not unusual for it to be mistaken for cardiac issues, especially when chest discomfort is involved. The presence of high paraprotein (IgG) and Bence Jones protein in the urine can indeed cause significant kidney problems, but it’s encouraging that your paraprotein levels have dropped significantly with DVTd treatment and that your rib pain has improved.
Bortezomib-based regimens like DVTd have shown good results, not only in controlling the underlying disease but also in helping reverse paraprotein-induced kidney injury in some patients, especially when started promptly
. Ongoing close monitoring of your kidney function and paraprotein levels with your medical team is key
. Peripheral neuropathy is a known side effect of some of these medications, so working with your doctors to manage and minimize these symptoms is important.
Keep communicating any new symptoms or concerns to your team, especially regarding your kidney function or nerve symptoms. Wishing you continued improvement with your treatment.
