New directions in myeloma research

This topic contains 2 replies, has 2 voices, and was last updated by  Mothas 11 years, 7 months ago.

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  • #94678

    Mothas
    Participant

    On the International Myeloma Foundation site they have started a research initiative called 'black swan research' into how to develop new and much more effective tests for myeloma, with the view of developing a complete cure. Looks promising and fingers crossed.

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    [b]Introducing the IMF?s Black Swan Research Initiative?[/b]
    Understanding that the search for a cure for multiple myeloma demands constant innovation, the IMF has launched the Black Swan Research Initiatve?, a unique project to develop the first definitive cure for myeloma. Led by a multinational consortium of leading myeloma experts, we are bridging the gap from long-term remission to cure.

    Why ?Black Swan??
    The Black Swan Research Initiative takes its name from the discovery of black swans in 1697, when it was assumed all swans were white. Just as people who had only seen white swans could not imagine the existence of black swans; until very recently, we could only imagine the possibility of finding a cure in our lifetimes. Through the Black Swan Research Initiative, we may soon see the first myeloma patients restored to a normal, healthy life, free of their cancer for the first time ever.

    What is Minimal Residual Disease (MRD)?
    When a patient is diagnosed with multiple myeloma, conventional wisdom thinks of it as one disease when in reality there are multiple diseases in one. There are many clones of multiple myeloma cells that are present in the same patient. Current treatments for myeloma target the dominant clones, but often leave behind some of the more resistant clones, which may lead to relapse down the line. These leftover cells are the Minimal Residual Disease, or MRD.

    Defining the Cure: MRD-Zero?
    Cancer cures are predominantly defined by waiting a fixed number of years post-remission to see if any cancerous cells emerge. Now, with a new understanding of myeloma at the molecular level, the IMF?s Black Swan Research Initiative is developing ultra-sensitive tests to accurately measure Minimal Residual Disease and define its absence as a cure.

    http://myeloma.org/PortalPage.action?tabId=8&menuId=125&portalPageId=18

    #94679

    bandityoga
    Participant

    Good to know that a cure is being sought.

    Donations are needed to keep up the good work.

    Maureen

    #94680

    Mothas
    Participant

    Yes from what I can glean from the project it's about finding much more effective ways of tracking the hidden components of myeloma that can ambush at later stages. In doing so they can target treatments much earlier and blatt the little buggers effectively clearing out the residual disease.

    So this is progress in testing regimes which in combination with the new drugs we'll see much more targeted and effective treatments. Good news all round.

    tom

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