[jomjo75Participant]

Hi everyone

I was diagnosed with Myeloma in October last year and began treatment in January 2026.
I am receiving one of the new treatments, Isa-VRD. It consists of six 4-week cycles, back to back, so is intense. I’m struggling with some of the side effects and wonder if anyone else is receiving this treatment?
The good news is that my serum light chains and paraproteins have plummeted so it’s doing what it’s supposed to.
Isa-VRD consists of Isatuximab, Bortezomib (Velcade) Dexamethasone and Lenalidomide.
Owing to my age I won’t be having SCT.

[rabbitParticipant]

Hi and welcome to the forum.

As you say yourself, Isa-VRd is relatively new, so not many people have had it yet.

I had DVRd in 2023, with D = Daratumumab, which is similar to Isatuximab (both are immunotherapy targetting the CD38 antigen in myeloma cells). I am still in remission.

What side effects are you experiencing?

Regards
Rabbit

[Author]

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