Of Carfilzomib…

This topic contains 6 replies, has 4 voices, and was last updated by  BADGER 12 years, 4 months ago.

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  • #93076

    DaiCro
    Participant

    [quote]The positive recommendation by the FDA Cancer Drugs Advisory Committee brings carfilzomib a step closer to being licensed and marketed as a treatment for relapsed and/or refractory myeloma patients in America. A final decision by the FDA is expected by the end of July 2012. The FDA approval of carfilzomib should hopefully be followed by its approval by the FDA?s European counterpart, the European Medicines Agency (EMA), later in the year. 😀

    Eric Low, Chief Executive of Myeloma UK said, ?This is great news for the myeloma community. As myeloma is largely a relapsing, remitting cancer, it is very important that the next treatment is always available. If these next treatments are both more effective and have fewer side-effects, then this is very important for patients. I sincerely hope the final decision is positive and that European approval follows soon.?[/quote]

    So, [b] Carfilzomib[/b] looks like it will soon be joining us in the fight against MM. The sooner the better to my mind. It is a cousin of [b]Velcade[/b]… but with better results and much gentler side-effects by all accounts. I know that I have been pushing [b]Carfilzomib/Kyprolis[/b] to the fore recently.. but I truly believe it will me a major step forward for us and the general fight against MM. 😎 😀 🙂

    Bring it on… quickly please.;-)

    Dai.

    [b]Footnote:[/b]

    Produced by the US Pharmaceuticals company [b]Onyx[/b], when fully licensed [b]Carfilzomib[/b] will be traded as [b]'Kyprolis'[/b].

    The quoted section above is part of the news of [b]Carfilzomib/Kyprolis[/b] to be found in the [b]'Home'[/b] section of this site.

    #93077

    andyg
    Participant

    Hi Dai
    I don't know if you use twitter but after a bit of hunting you can find some very useful links to reports from the US on there. I find it very useful. I now follow several posters from the US and get the latest news from over there.

    Andy

    #93078

    BADGER
    Participant

    Hello Dia
    This is good news for me if this drug is in the velcade family it will be prccessed through the liver which is good for me as my kidneys will not take all kinds of other drugs:-)
    Hope you are feeling well;-)
    Love Jo

    #93079

    DaiCro
    Participant

    Hi Jo,

    It's good to see and hear from you… on Bridget's funeral day I like to see that all my friends are out and about and as good as can be. 😎 🙂

    As I understand it, after being corrected by Ellen, Velcade is a cousin of Carfilzomib and not, as I erroneously posted earlier, a cousin of thalidomide. (But I'm still going to check that up).;-)

    In which case it looks like a good option for you… of course, as things stand Carfilzomib is not taken in isolation (though that might change)… at the moment it is taken in conjunction with Revlimid & Dex. Apperently Carfilzomib acts in the same way as Velcade and caps the cancer cells so they ilope with nowhere to go. The results are apparently much better than Velcade with significantly fewer side-effects. Carfilzomib actively brings the PP's/Light Chains right down and out of sight. “““when the course finishes the user carries on with Rev & Dex with a clear playing field… extending the lifespan and efficacy of that treatment.:-D

    There may be other plans for the drug, including frontline or single use, we will have to wait an see.:-)

    But it certainly looks promising.8-)

    Dai.

    #93080

    BADGER
    Participant

    HeIlo Dia
    I am not doing to badly but have a consultant app on monday so we will see I didnt really want to post after hearing about Bridget because her death upset me so much I had been in touch with her on E mail these last couple of years and felt I knew her quite well but she would not want us to give up so I will carry one:-(
    Love Jo x

    #93081

    tom
    Participant

    ((((hugs)) Jo I hope your Ok xxxx

    #93082

    BADGER
    Participant

    Thanks Tom
    A big (((hug)) to yoy too;-)
    Love Jox

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