Although it’s worrying when any parameters start moving outside normal ranges, it doesn’t seem to necessarily indicate progression.
Someone in my local support group had gradual increases in paraprotein levels over 8 months to the point that she was told re-treatment would be necessary, but at her pre treatment test it had fallen slightly so treatment was delayed. Her paraproteins continued to decline over the next few tests, and whilst they yo-yo, She still isn’t on treatment 18 months later.
I’ve got IgG lambda myeloma but my kappa levels have been high, outside normal parameters, since SCT (Feb 2019). My uninvolved kappa lightchain graph results are long 12 month curves between 35 & just about normal. The lambda (involved light chain) yoyo ed alot over the first year, then was stable (though now might be rising above the normal range)
About a year after SCT my ratio was slightly above the normal range, like your father’s, but has since had a downward trend, more or less to mid normal range.
If my results are anything to go by, it would seem your father’s may be pretty normal. I hope so, but one to check out with his consultant.
