Hi Deborah
My mum was recently invited to be part of the Myeloma X trial too. Although it wasn't an easy decision at all, she has decided to be in the trial. She hasn't started treatment yet, so I'm afraid I can't give you any specifics about side effects etc; however, I understand that doxorubicin is quite an intensive chemotherapy and we're expecting the treatment to be tougher than her induction treatment prior to SCT (which was CTD). The main reason for her decision to be part of the trial was that, from the info we could obtain, the addition of a chemotherapy drug to dexamethasone and velcade appears to increase the chances of response quite significantly. (We went to the London myeloma info day last Autumn and one of the haemotologists talked about this.) My mum's hospital doesn't offer the chemo on top of Velcade/Dex without going on the trial, but I know that some other hospitals do…
Hope this helps a little.
Best wishes
Mary
