Hi Claro70,
I am one of the new discussion forum volunteers and have just come across your post. I appreciate it was some time ago so I hope that your husband is doing much better now.
I wanted to share my experience due to some similarities so hopefully help you feel you’re not alone in this. My dad had his first SCT back in 2013 and went into remission until late 2020 when he relapsed. He was put on new treatment which he seemed to respond to initially, and as his first treatments in 2013 had gone so smoothly we didn’t expect it to not work, but then dad started to experience bad side effects about 3 months in, had his regimen tweaked and then it stopped working. He was without any treatment for a short time, which was worrying in itself as we knew while nothing was happening his bloods were going to be going crazy. Dad is now into his second cycle of lsatuximab and we see the consultant week after next so hoping that will have some positive effect and blood results will be improved. The positive is he’s feeling much better on the new combination even with the expected side effects, and has put on some of the weight he lost last year, so that is something!
Good luck with everything x