My mother is 70' years's old she went from mgus in the 2009 evolved
first in smouldering myeloma then to symptomatic myeloma with anemia
in the october 2012 she start teraphy with rev + dex a few moths ago undergo only three cycle after reaching remission with a 30% reduction of monoclonal component, we have reached a still point, with a slight increase of the monoclonal peak,then FISH showed chromosomal abnormalities 1q21 and t414 suddenly after this suffered an intestinal stroke, caused by occlusion, and underwent removal surgery.
After this dismissed treatment with rev+dex
the doctors propose 3 PAD cycle followed by double ASCT,
but there is a problem that worries me:
the Doxorubicin that is probably going to be used is the traditional one, not the liposomal one I don't want to run unnecessary risks,
though I am aware that the Doxorubicin problem is given
by the cumulative dose, and my mother should only undergo three cycles, but if we are unable to collect enough stem cells,
the number of cycles would increase, and so would the
heart complication possibilities.
I also read that there are other side effects, such as Neutropenia,
vomit, etc, in smaller percentages.
Do you think it's important for her to receive the liposomal Doxorubicin?
Do I need to consider taking my mother to another centre?
We have a great relationship with this current structure, but after 20 days in the hospital for intestinal complications, I don't want any further problems for my mum if they are not strictly necessary, and I could avoid at least part of them
My mother is not convincted at the idea of changing hospital but i'm very
scared with the possible side effects
What is the right choice leave her in the hospital were receive their care
now and where she knew physician and nurse or go away and start from zero
for the best treatment?
Please help me i don't no what to do