Hi Christine and welcome I am sure you will find this site as invaluable as I do. Sorry I cant be much help re collapsed vertebrae though. In my case I had 3 vertebrae completely dstroyed before being diagnosed, the doctors used to shake their heads in amazement because I was walking around , mind you the year of absolute agony was no fun Before I had any treatment for myeloma I had surgical reconstruction to my spine which involved metal plates and rods on three quarters of my back. Because the diagnosis took so long I have very extensive bone damage and as a result Iam not able to walk far or stand for too long and I have been on varying doses of morphine from the beginning. I hope they can do something to help , the vertoblasty sounds promising and I hope you get good news about your Velcade treatment tomorrow Please let us know how you get on Best wishes Bridget