Hi Sarah, all that i can tell you is that my Mum had revlimid for just 2 cycles and it knocked the myeloma back a few months, if her liver could have coped then she would have had it for more cycles and it might have given her a slightly longer remission, everybody is different in the way their bodies cope, i really hope that your Mum and my Mum make it through Christmas, my Mum is soon to start on more chemo maybe cdt not sure if it will help as she has had rcd but we hope. I had to smile when you mentioned that your Mum did not want to upset Christmas as my Mum is the same what great Mothers they are always thinking of the family, you are not alone, love San xx