Does Light chain increase matter if ratio is still normal?

This topic contains 3 replies, has 2 voices, and was last updated by  mulberry 1 year, 7 months ago.

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  • 1st September 2022 at 12:01 pm #146809

    sachbarnes
    Participant

    Dads Kappa increased to 10>30, and Lambda 7>19, so ratio still normal at 1.57.

    Cant seem to find much info online on if its of any importance. Anyone know?

    Tx

    2nd September 2022 at 7:40 am #146814

    mulberry
    Participant

    Hi Sachbarnes
    I believe it’s only the ratio that is of real significance.
    Since my SCT 3 1/2 years ago my kappa levels have been outside normal limits (high) despite me having lambda myeloma. My consultant has said that this is, if anything, a positive thing. The ratio is within normal range.
    Even if we are in a stable position disease wise, or if no myeloma is evident, our bone marrow remains ‘abnormal’ so perhaps that is the explanation.

    6th September 2022 at 1:11 am #146831

    sachbarnes
    Participant

    Thanks as always Jane. Most valuable person on the forum imo.

    6th September 2022 at 8:47 am #146832

    mulberry
    Participant

    Thank you, we all have our parts to play.
    I hope your father is feeling well.

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