It must be very disappointing to have not responded to a stem cell transplant. DVD is the comparatively new standard second line treatment for myeloma. It is a massive improvement on the old options and many UK myeloma patients are currently benefiting from it. Some patients with myelomas that have had little response to earlier treatments now have inactive or stable disease. Daratumumab, the first D in DVD, targets the cancer cells in a different way, and although patients can have side effects after the first dose, its reputation as an ongoing treatment looks good. It has certainly helped some people who were very despondant, either because they had not responded to earlier myeloma treatment or who had had extreme side effects. I hope it works well for you, please let us know how you get on.