[davebazParticipant]

I first raised the issue of pins and needles (peripheral neuropathy) last June (see above). Subsequently I developed occasional (one or two episodes per week) of sharp stabbing cramp like pains in one leg lasting 10 – 15 mins. Since then my consultant suggested a course of amitriptyline; an antidepressant drug which has been found of value in treating trigeminal neuralgia and the topical pain associated with shingles. I was started on a lowish dose of 20 mg each night and did think that my discomfort was helped. The dose was increased after several weeks to 40mg nocte following which I have had no more of the acute stabbing pains and the pins and needles have largely abated. I cannot be 100% certain that the amitriptyline is responsible for these improvements and would like to hear if anyone else has had similar findings with this drug

[davebazParticipant]

I am a 79 yr old male diagnosed approx 18 months ago with Stage 2 lymphoma/myeloma (IgG light chain) with ribcage lesions and a small pulmonary embolism. I received 8 cycles of Velcade, cyclophosphamide /dexamethasone and Zoledronic acid. Approx. 9 months ago I developed bronchial pneumonia and was hospitalised for 7 days whilst undergoing treatment with antibiotics. I responded well and I am currently now in ”remission” (hamatology status ‘normal’). But more recently, I have developed painful changes (pins and needles )in both heels and more recently quite severe spasmodic pain in my left foot which fits a decription of planar fascitis. This comes and goes unexpectedly and the pain prevents sleep. It only partialy responds to morphine / paracetamol. I would value hearing from anyone with similar painful condition presumably a consequence of a peripheral neuropathy. My consultant has not, so far, been able to suggest any other analgesic treatment.

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